Surgery in and of itself creates a controlled injury to your body's tissue. Fortunately, your body is equipped with healing mechanisms that begin a multi-stage healing process the moment the injury occurs. Proteins found within your body's bloodstream react like a response team and start performing a multitude of activities to stop bleeding, attract infection fighting cells and initiate new cell formation.
Platelet Gel is a substance that is created by harvesting your body's own natural healing factors from your blood and combining it with thrombin and calcium to form a coagulum.This coagulum or "platelet gel" has an extremely wide range of clinical healing uses from dental surgery to orthopedics and plastic surgery.
Platelet Gel is 100% biocompatible and safe. It poses absolutely no infectious risk to because it is made from your own blood.
Platelet Gel is a widely used and globally accepted safe, simple, and effective treatment modality for various surgical procedures and non-healing wounds.
New and emerging technologies have embraced the current use of Platelet Gel for various types of wound repair. Researchers have identified the importance of growth factors and how it dramatically influences the natural course of wound repair. These growth factors began with platelet-derived growth factor (PDGF), transforming growth factor (TGF) and the subsequent identification of many other growth factors now kn own to be important for active wound repair. Research has demonstrated that platelets contain a rich source of multiple growth factors within the alpha granules, which are secreted after activation with thrombin. Platelet counts in excess of 500K/ul suspended in plasma with a native fibrinogen concentration can lead to improved surgical hemostasis and faster wound healing.
Platlet Gel is 100% biocompatible and safe.
Prior to starting surgery, approximately 60 ml of blood is taken form the patient. This small blood volume is then placed into a tube and spun in a high speed centrifuge. This process automatically separates the blood into several different components, one of which we refer to as the "buffy coat" or platelet rich plasma.
On activation with thrombin/calcium to form a coagulum, the platelets iuntertwine with the forming fibrin web and immediately release highly active vasoconstrictors.
The resulting Platelet Gel contains up to a 4-10 time increase of your natural platelets, white blood cells, and healing factors with the adhesiveness and strength materially greater than the plasma alone.
This concentration of "Platelet Rich Plasma" enriches the natural clot to initiate a more rapid and complete healing process.
In addition to platelets, Platelet Gel also contains elevated levels of all your natural occuring growth factors. These factors are responsible for stimulating new cell growth and increasing the rate of wound healing
The physiological components of platelet gel consist of:
PDGF (Platelet derived growth factor)
TGF-a&b (Transforming growth factor alpha and beta)
EGF (Epidermal growth factor)
FGF (Fibroblast growth factor)
IGF (Insulin growth factor)
PDEGF (Platelet derived epidermal growth factor)
PDAF (Platelet derived angiogenesis factor)
High concentration of leukocytes (Neutrophils, eosinophils) for micobicidal events
High concentration of wound macrophages and other phagocytic cells, for biological debridement
Histamines, Serotonin, ADP, Thromboxane A2, and other vasoactive and chemotactic agents
High platelet concentration and native fibrinogen concentration for improved hemostasis
These growth factors which replace, repair, and regenerate tissue are considered by many to be a "new frontier" of clinical treatment. Increasing the bioactivity at the wound site takes medicine one step closer toward its ultimate goal of naturally accelerating the body's normal healing process.
Reported benefits from the use of Platelet Gel include: